Genetic test for celiac disease

What is the genetic test for celiac disease?

The genetic test for celiac disease is responsible for checking whether a person has a genetic predisposition to develop celiac disease, or whether, on the contrary, his or her genes will not develop this pathology. In other words, this test is not used to diagnose whether or not a person is celiac, but to establish whether celiac disease can develop thanks to our genes.

If the person does not have genes linked to celiac disease, it is very unlikely that this disease will develop, although other pathologies related to gluten may develop.

What does it consist of?

Genetic predisposition to celiac disease is related to the presence of the HLA-DQ2 heterodimer. This test consists of determining whether this marker exists in the patient’s genes; if it is positive, the patient is most likely to develop the pathology. If the test is negative, it is most likely that you will not develop celiac disease.

This test is recommended when a family member has been diagnosed with celiac disease.

Why is it performed?

This test is recommended when a family member has been diagnosed with celiac disease. In this way it will be possible to see if parents and/or siblings may become celiac or to rule out this pathology in the future.

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In many cases, even if there is no direct celiac disease in the family, it is possible that extra-digestive symptoms of celiac disease or even asymptomatic celiac disease may develop, so it is important to perform this test to rule out pathologies.

Preparation for the genetic test for celiac disease

Depending on the test to be performed, by saliva or blood test, the specialist will tell you how to proceed.

How do you feel during the test?

The test is simple and painless and can be done by a simple blood test or by analyzing the cells of the buccal mucosa.

For the blood test, blood is drawn from the inside of the arm. In addition, a tourniquet is used on the upper arm to decrease blood flow and allow the vein to swell. Before the needle is inserted, the skin is cleansed and the needle is then injected into the vein. The sample is then withdrawn, the needle is removed, and the wound is covered with a small piece of gauze.

What abnormal results mean

If the results are abnormal, the person will most likely develop celiac disease over time. This is because the person has genes that are related to celiac disease.

On the other hand, in most cases, if the results are normal, it is automatically ruled out that the person may have celiac disease.

If you need to take a celiac test, you can buy it online and choose the laboratory closest to you.